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Adoptive T-cell immunotherapy is a rapidly growing field and is shifting the paradigm of clinical cancer treatment. In addition, we review the CD19 chimeric antigen receptor T-specific toxicities of cytokine release syndrome and neurotoxicity, which remain the challenges to the safe delivery of this important therapy for aggressive B-cell lymphomas with poor prognosis. The prognosis of aggressive B-cell lymphomas is based on clinical, molecular and genetic factors as well as responsiveness to induction chemotherapy. The International Prognostic Index IPIbased on clinical features found at initial diagnosis age, stage, autl disease, performance status and lactate dehydrogenase elevation is historically the most widely used and is a powerful prognostic. Molecular profiling studies and next-generation sequencing have improved the understanding Langstrasse beautiful girls DLBCL and its heterogeneity, and may prospectively identify cases with high-risk features.

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Orr auto Lugano, dose-escalated immunochemotherapy is associated with a significant progression-free survival advantage in Orr auto Lugano with double-hit lymphomas: a systematic review and meta-analysis.

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Making better chimeric antigen receptors for adoptive T-cell therapy. View 1 Result.

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